Frauke Mattner

  1. Confidence bounds for the sensitivity lack of a less specific diagnostic test, without gold standard.

    Authors: Lutz Mattner, Frauke Mattner
    Subjects: Applications
    Abstract

    We consider the problem of comparing two diagnostic tests based on a sample
    of paired test results without true state determinations, in cases where the
    second test can reasonably be assumed to be at least as specific as the first.
    For such cases, we provide two informative confidence bounds: A lower one for
    the prevalence times the sensitivity gain of the second test with respect to
    the first, and an upper one for the sensitivity of the first test. Neither
    conditional independence of the two tests nor perfectness of any of them needs
    to be assumd.

Syndicate content