Victor M. Panaretos

  1. Sparse approximations of protein structure from noisy random projections.

    Authors: Victor M. Panaretos, Kjell Konis
    Subjects: Applications
    Abstract

    Single-particle electron microscopy is a modern technique that biophysicists
    employ to learn the structure of proteins. It yields data that consist of noisy
    random projections of the protein structure in random directions, with the
    added complication that the projection angles cannot be observed. In order to
    reconstruct a three-dimensional model, the projection directions need to be
    estimated by use of an ad-hoc starting estimate of the unknown particle.

  2. A Conversation with David R. Brillinger.

    Authors: Victor M. Panaretos
    Subjects: Methodology
    Abstract

    David Ross Brillinger was born on the 27th of October 1937, in Toronto,
    Canada. In 1955, he entered the University of Toronto, graduating with a B.A.
    with Honours in Pure Mathematics in 1959, while also serving as a Lieutenant in
    the Royal Canadian Naval Reserve. He was one of the five winners of the Putnam
    mathematical competition in 1958. He then went on to obtain his M.A. and Ph.D.
    in Mathematics at Princeton University, in 1960 and 1961, the latter under the
    guidance of John W. Tukey.

  3. On random tomography with unobservable projection angles.

    Authors: Victor M. Panaretos
    Subjects: Statistics
    Abstract

    We formulate and investigate a statistical inverse problem of a random
    tomographic nature, where a probability density function on $\mathbb{R}^3$ is
    to be recovered from observation of finitely many of its two-dimensional
    projections in random and unobservable directions. Such a problem is distinct
    from the classic problem of tomography where both the projections and the unit
    vectors normal to the projection plane are observable. The problem arises in
    single particle electron microscopy, a powerful method that biophysicists
    employ to learn the structure of biological macromolecules.

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