David Borsook

  1. A simple and objective method for reproducible resting state network (RSN) detection in fMRI.

    Authors: Gautam V. Pendse, David Borsook, Lino Becerra
    Subjects: Applications
    Abstract

    Spatial Independent Component Analysis (ICA) decomposes the time by space
    functional MRI (fMRI) matrix into a set of 1-D basis time courses and their
    associated 3-D spatial maps that are optimized for mutual independence. When
    applied to resting state fMRI (rsfMRI), ICA produces several spatial
    independent components (ICs) that seem to have biological relevance - the
    so-called resting state networks (RSNs). The ICA problem is well posed when the
    true data generating process follows a linear mixture of ICs model in terms of
    the identifiability of the mixing matrix.

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