Luca Bortolussi

  1. Programmable models of growth and mutation of cancer-cell populations.

    Authors: Luca Bortolussi, Alberto Policriti
    Subjects: and Science, Computational Engineering, Finance
    Abstract

    In this paper we propose a systematic approach to construct mathematical
    models describing populations of cancer-cells at different stages of disease
    development. The methodology we propose is based on stochastic Concurrent
    Constraint Programming, a flexible stochastic modelling language. The
    methodology is tested on (and partially motivated by) the study of prostate
    cancer.

  2. HYPE with stochastic events.

    Authors: Jane Hillston, Luca Bortolussi, Vashti Galpin
    Subjects: Logic in Computer Science
    Abstract

    The process algebra HYPE was recently proposed as a fine-grained modelling
    approach for capturing the behaviour of hybrid systems. In the original
    proposal, each flow or influence affecting a variable is modelled separately
    and the overall behaviour of the system then emerges as the composition of
    these flows. The discrete behaviour of the system is captured by instantaneous
    actions which might be urgent, taking effect as soon as some activation
    condition is satisfied, or non-urgent meaning that they can tolerate some
    (unknown) delay before happening.

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