Nicole Kraemer

  1. Optimal learning rates for Kernel Conjugate Gradient regression.

    Authors: Nicole Kraemer, Gilles Blanchard
    Subjects: Statistics
    Abstract

    We prove rates of convergence in the statistical sense for kernel-based least
    squares regression using a conjugate gradient algorithm, where regularization
    against overfitting is obtained by early stopping. This method is directly
    related to Kernel Partial Least Squares, a regression method that combines
    supervised dimensionality reduction with least squares projection. The rates
    depend on two key quantities: first, on the regularity of the target regression
    function and second, on the intrinsic dimensionality of the data mapped into
    the kernel space.

  2. The Degrees of Freedom of Partial Least Squares Regression.

    Authors: Nicole Kraemer, Masashi Sugiyama
    Subjects: Methodology
    Abstract

    The derivation of statistical properties for Partial Least Squares regression
    can be a challenging task. The reason is that the construction of latent
    components from the predictor variables also depends on the response variable.
    While this typically leads to good performance and interpretable models in
    practice, it makes the statistical analysis more involved. In this work, we
    study the intrinsic complexity of Partial Least Squares Regression. Our
    contribution is an unbiased estimate of its Degrees of Freedom.

  3. Kernel Partial Least Squares is Universally Consistent.

    Authors: Nicole Kraemer, Gilles Blanchard
    Subjects: Methodology
    Abstract

    We prove the statistical consistency of kernel Partial Least Squares
    Regression applied to a bounded regression learning problem on a reproducing
    kernel Hilbert space. Partial Least Squares stands out of well-known classical
    approaches as e.g. Ridge Regression or Principal Components Regression, as it
    is not defined as the solution of a global cost minimization procedure over a
    fixed model nor is it a linear estimator. Instead, approximate solutions are
    constructed by projections onto a nested set of data-dependent subspaces.

  4. Regularized estimation of large-scale gene association networks using graphical Gaussian models.

    Authors: Nicole Kraemer, Juliane Schaefer, Anne-Laure Boulesteix
    Subjects: Methodology
    Abstract

    Graphical Gaussian models are popular tools for the estimation of
    (undirected) gene association networks from microarray data. A key issue when
    the number of variables greatly exceeds the number of samples is the estimation
    of the matrix of partial correlations. Since the (Moore-Penrose) inverse of the
    sample covariance matrix leads to poor estimates in this scenario, standard
    methods are inappropriate and adequate regularization techniques are needed.

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